ENTRANCE AND SPREAD OF BACTERIA. 



195 



children have been described in which the bacillus pyocyaneus 

 has been found throughout the body ; in these cases the chief 

 symptoms have been fever, gastro-intestinal irritation, pustular 

 or petechial eruptions on the skin, and general marasmus. 



Suppurative and inflammatory conditions, associated with 

 the organisms of special diseases, will be described in the respec- 

 tive chapters. 



Mode of Entrance and Spread. Many of the organisms of 

 suppuration have a wide distribution in nature, and many also 



are present on 



***/*"- 

 the skin and mu- 

 cous membranes 



of healthy indi- . : '.'/. 



viduals. Staphy- 

 lococci are com- 

 monly present * , '..'*"<-. 

 on the skin, and -v^; 

 also occur in the 

 throat and other *. ^ , 

 parts, and strep- .^ 

 tococci can often 

 be cultivated 

 from the secre- 

 tions of the '" ' ' - ' : 



/. i*+ ~ .- ' . ' 



mouth in normal 'Ufc*^* ' : "" 



conditions. The 



pneumococcus 



of Fraenkel and ^ IG ' ?3 - Minute focus of commencing suppuration in 



brain case of acute ulcerative 'endocarditis. In the centre a 



the pneumoba- small haemorrhage; to right side dark masses of staphylococci ; 



cillllS Of Fried- Z0ne of leucoc y tes at periphery. 



Alum carmine and Gram's method. X 50. 



lander have also 



been found in the mouth and in the nasal cavity, whilst the 

 bacillus coli communis is a normal inhabitant of the intestinal 

 tract. The entrance of these organisms into the deeper tissues 

 when a surface lesion occurs can be readily understood. Their 

 action will, of course, be favoured by any depressed condition 

 of vitality. Though in normal conditions the blood is bac- 

 terium-free, we must suppose that from time to time a certain 

 number of such organisms gain entrance to it from trifling 

 lesions of the skin or mucous surfaces, the possibilities of 



