104 BACTERIOLOGY 



Staphylococcus citreus, and also of all three combined, 

 for the treatment of infections where all three exist 

 together. Each cubic centimeter contains 400,000,00x3 

 bacteria. The dose should be about 100,000,000 to 

 begin with, and increased according to the patient's 

 tolerance. Five to eight days should elapse between 

 doses. 



Streptococcus Vaccine. This has been used with 

 rather meager results. Some benefit is claimed for it 

 in sepsis and in scarlet fever, but the benefit derived 

 from its use is less than from most any of the bacterial 

 vaccines. Doubtless the variety of strains of this germ 

 or its varying behavior under differing conditions may 

 account for the lack of success of vaccine therapy in 

 treating infections with it. 



Gonococcus Vaccine. This has been used with good 

 results in the chronic form and in the complications of 

 this disease, as in arthritis, prostatitis, endocarditis, 

 etc. Its value as an immunizing agent has, fortunately, 

 not been established. 



Bubonic Plague Vaccine (Haffkine's Prophylactic). 

 This vaccine is produced by growing Bacillus pestis 

 upon broth. After the growth has proceeded for a 

 month or six weeks, the culture is sterilized by heating 

 and tested for sterility upon mice, when it is ready for 

 use. 



Administration and Dosage. The dose is from i to 

 3 c.c., administered by injection. The administration 



