TUMORS 151 



fibroma. The most important of these forms of growth 

 are the amputation neuromata, occurring at the site 

 of amputations. They also occur along the course of 

 nerves, independent of amputation or injury. 



Lymphadenoma. This is a malignant form of growth 

 composed of lymphadenoid tissue. It occurs in the 

 lymphatic glands and other adenoid tissues. The exact 

 relation of this form of tumor growth to Hodgkin's 

 disease is not well understood. It is probably one 

 manifestation of this disease. 



Lymphosarcoma. Lymphosarcomata are simply the 

 forms of lymphadenomata which partake of the char- 

 acter of sarcoma. It is doubtful if there exists any 

 material distinction between lymphadenoma and 

 lymphosarcoma. They are both probably forms of 

 sarcoma. 



Sarcoma. Sarcomata are malignant growths com- 

 posed of connective tissue closely resembling the embry- 

 onal type, having an abundance of cells and little inter- 

 cellular substance. Sarcomata always arise from meso- 

 blastic tissue, as bone, cartilage, or connective tissue. 

 They occur in the bones, periosteum, brain, liver, lungs, 

 and intestines. They most frequently affect children 

 or young adults. They form metastases through the 

 circulation, recur after operation, and are always 

 fatal. 



Various forms are designated according to their 

 histologic structure, such as spindle-celled sarcoma, 



