222 MODES OF ACTION. 



to endocarditis, etc. Again, mixed infection may be induced by 

 injecting simultaneously into susceptible animals two species of path- 

 ogenic bacteria. 



Bumm, Bockhart, and others have reported cases of mixed gonor- 

 rhoeal infection in which the pyogenic micrococci gave rise to ab- 

 scesses in the glands of Bartholin, to cystitis, parametritis, or to 

 " gonorrhoeal inflammation " of the knee joint. Babes gives numer- 

 ous examples of mixed infection in scarlet fever and in other diseases 

 of childhood. Anton and Fiitterer have studied the question of 

 secondary infection in typhoid fever. Karlinski has reported a case 

 of secondary infection with anthrax in a case of typhoid fever, infec- 

 tion occurring by way of the intestine. Many other examples of 

 secondary or mixed infection are recorded in the recent literature of 

 bacteriology and clinical medicine, but enough has been said to call 

 attention to the importance of the subject. 



