PHYSICAL CHARACTERS IN MAN 55 



and body covered with long hair. This was accompa- 

 nied by deficient teeth. He also refers to a woman with 

 completely hairy face, exhibited in London in 1663. 



E. Fischer (1910) has given the history of an 

 interesting family in Upper Alsace, near Colmar, 

 some of whose members were almost entirely devoid 

 of hair. Daniel BoUenbach, belonging to the second 

 generation of the pedigree (see Fig. 10), had no hair 

 of the ordinary type, but his whole head bore a very 

 scattered, soft down, about i centimetre long, com- 

 posed of soft, thin, colourless hairs. Under the 

 microscope they are seen to have no central medulla 

 or pigment granules, to be somewhat thinner than 

 ordinary hair, and twisted. Amongst these are a very 

 few longer (3 centimetres) and somewhat thicker, 

 pale reddish, delicate hairs. Under the microscope 

 these show a normal central medulla and a weak 

 reddish-brown pigmentation. Eyebrows and e3^e- 

 lashes are lacking. The arms and legs are hairless ; 

 also there is no breast hair or axillary hair. The 

 nails of the toes and fingers are deformed, becoming 

 thick and rough. The teeth deca\'ed early, leaving 

 many stumps. There is here the well-known corre- 

 lation between deficiencies in teeth, nails, and hair. 

 Some other members of the familv have a few hairs 

 on the body = 



The inheritance of this hairless, condition shows 

 peculiarities (see chart. Fig. 10), which are difficult to 

 explain except perhaps on an hypothesis of variable 

 or reversed dominance of a single Alendelian factor. 

 The character itself seems to have appeared suddenty 

 through a germinal change, since the two generations 

 preceding its original appearance were all normal, 

 although they included cousin marriages which would 

 probably have brought out a recessive character it 

 it had been present. It will be seen (Fig. 10) that in 

 the Fi Mathias, who was normal, had only normal 



