688 



DISEASES OF THE SKIN. 



made to move, it did so very stiffly, and gave evidence of 

 pain, arising from friction of the excoriated surfaces and move- 

 ment of the rigid swollen and tender skin ; the limbs became 

 more pronouncedly swollen, but at no time was the swelling 

 very great. 



Throughout the course of the disease, and in all cases seen 

 by me, the bowels were rather constipated, the faeces being hard, 

 dry, and pellety, and covered over with a slight mucosity. 



Fig. 122.— Kidney. Boundary layer transverse to tubules, which are 

 partly denuded of epithelium, some of which may be accidental, but 

 remaining cells are similarly changed to above, (x 350.) 



On examination of the liver, kidneys, and skin — the only 

 organs which gave evidence of disease on post viortem exami- 

 nation — the liver had a soft and degenerated appearance, tb^ 

 kidneys were slightly enlarged, soft, and pale, the skin 

 thickened. 



The Skin. — The surface layers of the epidermis were largely 

 desquamated, and the papillfe of the derma hypertrophied. 

 There was enlargement of the sebaceous follicles, which were 



