CROTALUS HORRIDUS. 



with a scruple at least of fine sac lac, made a paste of this 

 with about a dozen drops of filtered rain-water, and intro- 

 duced on a clean vaccine point some of the poison thus pre- 

 pared into three punctures made by a lancet on the front of 

 the left fore-arm ; also rubbed some minute portions of the 

 sac lac, hardened by the poison, into one of the wounds : 

 this was done at 9.30 A. M. 



Indefinable sensation of all-overishness (sorte (Penvahisse- 

 ment), with a lightness in the head (entreprise generate) , slight, 

 lasting perhaps half an hour. 



11.15 A. M. Slight aching in fourth and little finger of 

 right hand, followed in a quarter of an hour by peculiar sen-, 

 sation as of thumbing (fouillement) in the middle of triceps, 

 left arm. 



12.30. Again inoculated the fore-arm, and made a new 

 wound in upper arm (left). 



Fine tingling in legs and feet while standing. 



Slight aching in the back part of thighs : afternoon. 



Tired feel in the cervical and dorsal vertebrae, with the 

 peculiar burning often attendant on exhaustion, all day. 



Kind of burning pressure on a point at back of pharynx 

 several hours this afternoon. 



Pressing and drawing sensations on points in lower limbs 

 and feet several times. 



Nov. 8. 2d day. Hard pressure on chest just above right 

 nipple, afternoon. 



3d day. Rheumatic drawing in left shoulder, morning. 

 10 A. M. Inoculated thoroughly well a puncture in left up- 

 per arm with the poison paste and felt immediately : 



The same all-overishness as on Sunday, lasting half an 

 hour. 



Dull shoots up occiput. 



Very fine prickling in left eyebrow. 



Is affected easily by a very little wine or alcoholic drink 

 during the week. 



Sleep broken and disturbed, during the week. 



" Second Experiment. 



Nov. 8, 1852. 1st day. Rosa, tall, robust, of full form, 

 sanguine temperament, aged nineteen, menses normal. 

 This morning, inoculated in the right upper arm. 



13 



