OTHER DISEASES OF DOMESTIC ANIMALS. 149 



absolutely secured from infection, whatever be the mode 

 of inoculation, and the intensity of the virus. All the 

 other test dogs which were inoculated at the same 

 time died of rabies. In 1884, Pasteur found the means 

 of attenuating the virus. For this purpose he has 

 inoculated a morsel of the brain of a mad dog into a 

 rabbit's brain, and has passed the virus proceeding 

 from the rabbit through the organism of a monkey, 

 whence it becomes attenuated and a protective vaccine 

 for dogs. This is the first step towards the extinction 

 of this terrible disease. 



VII. GLANDERS. 



This, again, is a disease easily transmitted from 

 horses to man. Glanders, or farcy, is caused by the 

 presence of a bacterium, observed as early as 1868 

 by Christot and Kiener, and more recently studied at 

 Berlin by Schiitz and Lofler. This microbe appears 

 in the form of very fine rodt (bacillus) in the lungs, 

 liver, spleen, and nasal cavity. Babes and Havas 

 found this bacillus in the human subject in 1881. 

 Experimental cultures have been made simultaneously 

 in France and Germany, and have given identical 

 results. 



Bouchard, Capitan, and Charrin made their cultures 

 in neutralized solutions of extract of meat, maintained 

 at a temperature of 37. By means of successive 

 sowings, they have obtained the production of un- 



