No. 4.] CATTLE COMMISSIONERS. 569 



up to one-half inch in thickness. Similar patches on abdominal aspect 

 of diaphragm and on spleen. Fewer patches on gall bladder and on the 

 liver. In one of the portal glands a one-qnarter inch focus, pale, grayish, 

 permeated with small, calcareous spicules. 



We have in these cases a wide divergence in the result of the 

 inoculation. The human bacillus produced a slight eruption of 

 small, tubercle-like bodies, which did not even present microscop- 

 ically the characters of true tubercles ; while the bovine bacillus 

 produced an exquisite case of pearly disease both in thorax and 

 abdomen, with the formation of large, grape-like masses in the 

 chest. These, under the microscope, presented all the characters 

 of genuine tubercles, and contained tubercle bacilli. 



The youngest sputum culture (No. III.) was injected into a 

 yearling weighing 410 pounds. At the end of two months the 

 weight had risen to 480 pounds. The lesions found are slight : — 



On the abdominal aspect of diaphragm, right side, a patch of isolated 

 tubercles about two inches in diameter, the tubercles themselves about 

 one-sixth inch diameter, and about one-half inch apart. They are 

 grayish, opaque. At place of inoculation, on serous aspect of ribs a 

 flattish neoplasm, one inch in diameter and about one-eighth inch, thick. 

 Other lesions not detected. 



In this case also the needle evidently entered abdomen through 

 diaphragm. The notes show very little disturbance as the result 

 of the inoculation. 



The swine culture was injected into a somewhat older animal, 

 weighing 620 pounds. After two mouths the weight was 660 

 pounds. The autopsy showed the following condition : — 



At place of inoculation (right chest wall) a subcutaneous tumor about 

 two inches in diameter, made up of a very dense connective tissue sac 

 one-quarter inch thick, and which encloses a pale, yellowish semifluid 

 mass. . . . There are besides this focus in the same situation three 

 smaller nodules, from one-half to three-fourths inch in diameter, the 

 largest with caseous centre. On the pleural aspect a similar one-half 

 inch centrally softened focus. 



In nearly the centre of the right half of diaphragm and projecting 

 into abdomen for one-half inch is a tumor representing a portion of a 

 larger focus in the muscular portion of the diaphragm about one inch in 

 diameter. This focus is likewise caseous diffluent centrally. On all the 

 ribs of right pleural cavity are eruptions of small tubercles, reaching in 

 some instances a diameter of one-eighth inch. Besides the palpable 

 tubercles there is along one border of each rib a line of vascular fringes 

 of connective tissue. In many of these fringes tubercles not noticed, 

 although the fringes themselves are evidently a result of the injection. 



