No. 4.] CATTLE COMMISSIONERS. 575 



In the spleen, all malpighian bodies converted into tubercles with 

 yellow, opaque centre. In left kidney several minute grayish tubercles. 



No. 8S (bovine culture IV.). — Red and white cow. Teeth very much 

 worn ; probably twelve years old ; dehorned. Not pregnant 



Thorax : No deposit at point of inoculation. The eruptions of tuber- 

 cles on the costal pleura of the right and the left side are in character very 

 much like those of the preceding case (No. 63), but less extensive. 



Right lung : Lobes adherent to pericardium. Adhesions readily 

 severed. On convex surface of the caudal lobe of this side a consider- 

 able number of flattish sessile tubercles, from one-sixteenth to one-half 

 inch broad. The caudal aspect of this lobe is similarly beset with them, 

 but in less abundance. Along the margin of this lobe are loosely 

 attached small elongated masses of tubercles 



At the same situation in this lobe as in the sputum cases there is a 

 fluctuating tumor, about two inches in diameter, slightly projecting. 

 It consists of a capsule with nearly smooth walls, enclosing a soft 

 caseous mass. It is surrounded by a zone of small necrotic tubercles, 

 and with lobules containing numerous minute grayish foci. 



On the cephalic lobe of the right lung a considerable number of gray- 

 ish tubercles. Throughout all lobes are many tubercles in the lung 

 tissue, some very minute, others larger and opaque, yellowish in color. 



The pleura iu the dorsal mediastinal space is beset with a large nvim- 

 ber of small tubercles, similarly the pericardium. The right half of 

 the diaphragm is beset with flattened aggregations of tubercles. Be- 

 tween the ventral lobe of the right lung and the pericardium, and fast- 

 ening them together, is a mass of newly formed connective tissue and 

 fat, enclosing numerous softened foci. 



The large dorsal mediastinal lymph gland is enlarged, and contains a 

 large number of yellow tubercles. The central portion of the gland is 

 uniformly caseous. In the left bronchial gland, a small number of 

 tubercles ; in the ventral mediastinal glands, a considerable number. 



Organs of the abdomen appear free from visible tuberculous changes. 



A summary of the outcome of this last experiment may now be 

 made. 



The points of difference between the inoculation disease pro- 

 duced by bovine and by human (sputum) bacilli are several: — 



1. The bovine cases either remained stationary in weight or 

 lost slightly, while the sputum cases gained seventy-five to eighty- 

 five pounds. Still, the age of one of the bovine cases ^ may be 

 partly responsible for stationary weight. 



2. There was marked fever in the bovine cases for three weeks 

 after the inoculation, practically none iu the sputum cases. 



3. There were well-marked differences in the lesions produced. 

 In the sputum cases the lesions are practically the same, and 

 consisted in : — 



(a) A tumor in the right caudal lobe of the limgs. about one inch in 

 diameter, projecting somewhat above the surface of the lung. This 



