576 BOARD OF AGRICULTURE. [Pub. Doc. 



represents the place where the needle penetrated into the lung tissue 

 and deposited the tubercle bacilli. In each case the contents of this 

 tumor were softened and converted into a curdy mass, enclosed in a 

 thin-walled capsule, smooth internally. The disease was not spreading 

 from this point, nor were tubercles visible in the lymph glands of the 

 lungs and thorax, excepting in one gland of No. 39. 



(b) The free margin of the right hmg, the pleural covering in part 

 and the pleural covering of the ribs on the right side were beset with a 

 new formation of loose vascular fringes or shreds, in which in only one 

 case some minute nodules could be felt, also some flattish pedicled 

 masses, not resembling tubercles. 



Among the bovine cases we have the following characteristic 

 points to note : — 



(«) Disseminated tuberculosis of the lungs, severest and fatal in No. 

 71, the youngest, least pronounced in the oldest. No. 88. Associated 

 with this, a local disintegrated focus in the lungs of No. 88. 



(&) Tubercvilar deposits on lungs, pericardium and diaphragm, and 

 the ribs, resembling closely the product of the natural disease in cattle. 

 The few pedicled masses attached to the pleura in the sputum cases 

 bore no direct resemblance to tuberculous outgrowths, although they 

 are undoubtedly the result of the inoculation. 



(c) Extensive tuberculosis of all or nearly all the lymph glands of 

 the thorax, including both mediastinal chains. 



(^cl) Tuberculosis of other organs, spleen, liver, kidney, in two out of 

 three cases. 



A summary of the three separate experiments, in which 12 

 animals Avere used , shows that : — 



6 animals were inoculated with human bacilli. 

 5 animals were inoculated with bovine bacilli. 

 1 animal was inoculated with swine bacilli. 



Of the 6 sputum cases : — 



1 showed no disease. 



2 showed very slight lesions. 



3 showed only local lesions without dissemination. 



Of the 5 bovine cases : — 



2 died of generalized disease. 



2 showed extensive lesions. 



1 s-howed less extensive lesions. 



In the swine case (probably originally bovine) the lesions were 

 less extensive than in the bovine cases. 



