No. 4.] CATTLE COMMISSIONERS' REPORT. 571 



pale and delicately houeycoinbed, the external irregularly nodu- 

 lated with small tubercles, undergoing caseation. This whole en- 

 largement contained five such cysts of different sizes. 



The lymphatic glands on either side of the trachea, and espe- 

 cially those near the point of inoculation, were enlarged to the size 

 of a horse-chestnut, and upon section showed necrotic areas and 

 calcification. 



In the lungs were several small, opal white nodules, scarcely 

 the size of a pin's head. These were mostly found in the ante- 

 rior lobe of the left lung. 



In the liver were several (fifteen to twenty) small, well-defined, 

 yellowish spots, as a rule pin-head in size, and mostly just beneath 

 the capsule ; only three such were found in the deeper parenchyma 

 of the organ. 



The microscopic examination of the above lesions showed them 

 all to be of a tuberculous nature. The tubercules in the lungs and 

 liver were exceedingly small, but perfectly typical in structure, 

 though it was only after prolonged search that one or two tubercle 

 bacilli were discovered. 



Calf IV. (two months old ; not tested ; not from tested 

 mother). — The inoculation was made into the trachea, as in the 

 preceding case. Tested with tuberculin at the end of five weeks, 

 this animal reacted as follows : — 



Degrees F. 



Time: 8.30 p.m. Kormal temperature, . . 102.0 



7.30 A.M. After injection, . . . .104.2 



9.30 a.m. After injection, . . . . 105.0 



11.30 a.m. After injection, . . . .104.3 



1.30 pm. After injection, . . . . 104.0 



3.30 p.m. After injection, . . . . 104.1 



Calf IV. was killed five months after inoculation, and the au- 

 topsy showed absolutely no lesions tvhatever. Nothing abnormal 

 could be found in the neighborhood of the point of inoculation, 

 and nothing suspicious was found elsewhere in the body, save a 

 very few yellow spots just beneath the capsule of the liver, and 

 two or three similar ones in the deeper tissue of this organ. 

 These were pin-head in size, and were thought to be tubercles 

 similar to those found in the liver of Calf III. ; but later micro- 

 scopic examination showed them to consist simply of an increase 

 in the connective tissue about some of the blood vessels and neigh- 

 boring bile-ducts, and in one instance a small abscess. (For the 

 possible explanation of the reaction of this calf to tuberculin, see 

 summary.) 



