Chap. VI .] CAR TIL A GE. 4 7 



dition of a layer or layers of hyaline ground substance ; 

 this is the most recently-formed part of the matrix, but 

 is still distinct 

 from the rest of 

 the ground sub- 

 stance. -j. 



56. In some 



places, especi- ^*& / 



ally in articular ^ 



cartilage (Till- 

 manns, Baber), 



bundles of fine . i |'< 



conne ctive *sp 



tissue fibrils 

 may be noticed 

 in the hyaline 



ground SUb- Fig . 30B. From a Preparation of Sternal 

 Stance. Cartilage of Newt. 



K*J TV, o/vmp The lacunae, containing the cartilage cells, anastomose 

 ^ ' -**"* ^^-" l>y fine channels* 



cartilages, the 



protoplasm of the cell becomes filled with fat globules 

 (Fig. 30c). This fact may be observed in many normal 

 cartilages ; sometimes the fat globules 

 become confluent into one large drop, 

 and then the cell has the appearance of 

 a fat cell. In age, disease, and defi- 

 cient nutrition, lime salts are deposited 

 in ^the ground substance, beginning 

 from the circumference of the cells. 

 The lime matter appears in the shape 

 j.soc.-Three car- of opaque granules, or irregular or 



ilage Cells filled , ^ i 2 i i 



nth Fat Droplets, angular clumps. The ground sub- 



From the hyaline , r 



cartilage of tho stance thereby loses its transparency, 



lineal septum of . / ., i i *; 



Guinea-pig. becomes opaque in transmitted, white 



in reflected, light, and, of course, very 



hard and brittle*. This process is the calcification of 



cartilage. It is also met with in cartilage that is to be 



