372 PATHOGENIC MICROORGANISMS 



nized, but also culled attention to the intracellular position of the micro- 

 organism and to its gonococcus-like appearance. They failed, however, 

 to cultivate it. 



Observations confirmatory of the Italian authors were, soon after, 

 made by Leichtenstern. 1 Cultivation and positive identification as a 

 separate species was not accomplished, however, until Weichselbaum, 2 

 in 1887, reported his observations upon six cases of epidemic cerebro- 



** 



. ..> ' +. ' 



li^ 

 w 



n 



*/ ^ 



A * % * 



% ^ 





FIG. 77. MENINGOCOCCUS, PURE CULTURE. (Very highly magnified.) 



spinal meningitis in which he not only found the cocci morphologically, 

 but was able to study their biological characteristics in pure culture. 

 The researches of Weichselbaum were soon confirmed and extended 

 by elaborate studies 3 which left no doubt as to the specific relationship 

 between the microorganism cultivated by him and the clinical condition. 



1 Leichtenstern, Deut. med. Woch., 1885. 



2 Weichselbaum, Fort. d. Med., 1887. 



3 Councilman, Mallory, and Wright, Special Rep. Mass. Board of Health, 1898; 

 Albrecht und Ghon, Wien. klin. Woch., 1901. 



