198 



HISTOLOGY 



methods, and eosin is a dye used in routine examinations, these cells are 

 often seen. According to Weidenreich the eosinophilic granules are mi- 

 nute fragments of red corpuscles, or products of their degeneration, which 

 have been ingested. Badertscher (Amer. Journ. Anat., 1913, vol. 15, 

 pp. 69-86) finds that eosinophiles are very numerous in the vicinity of 

 the degenerating muscle fibers in salamanders, during the time when 

 their gills atrophy. He agrees with Weidenreich that the eosinophilic 

 granules are not products of protoplasmic activity but are derived from 



ii. 



FIG. 187. THE BLOOD CORPUSCLES. (WRIGHT'S STAIN.) 



Clinical Hsematology.) 



(E. F. Faber, from Da Costa's 



I, Red corpuscles. II, Lymphocytes and large mononuclear leucocytes. Ill, Neutrophiles. 

 IV, Eosinophiles. V, Myelocytes (not found in normal blood). VI, Mast cells. 



material outside of the cells; and he likewise finds that they are taken up 

 by lymphocytes which thus become eosinophiles. Badertscher's work is 

 of interest in connection with cases of trichiniasis in man, in which the 

 number of eosinophiles in the blood becomes greatly increased, and at the 

 same time there is extensive degeneration of the muscles, caused by the 

 parasites. There is, therefore, reason to believe that esinophilic granules 

 are haemoglobin derivatives, but, as stated by Minot, "renewed investiga- 

 tion of the eosinophiles in man is very desirable." 



