CHAP, i.] BLOOD. 43 



Hence a part, and it may be no inconsiderable part, of the 

 body of a white corpuscle may be not living substance at all, but 

 either food or waste. Further it does not necessarily follow that 

 the whole of any quantity of material, fatty or otherwise, intro- 

 duced into the corpuscle from without, should actually be built up 

 into and so become part of the living substance ; the changes from 

 raw food to living substance are as we have already said probably 

 many, and it may be that after a certain number of changes, few 

 or many, part only of the material is accepted as worthy of being 

 made alive, and the rest, being rejected, becomes at once waste 

 matter ; or the material may, even after it has undergone this or 

 that change, never actually enter into the living substance but all 

 become waste matter. We say waste matter, but this does not 

 mean useless matter. The matter so formed may without entering 

 into the living substance be of some subsidiary use to the corpuscle, 

 or as probably more often happens, being discharged from the cor- 

 puscle, may be of use to some other part of the body. We do not 

 know how the living substance builds itself up, but we seem com- 

 pelled to admit that, in certain cases at all events, it is able in 

 some way or other to produce changes on material while that 

 material is still outside the living substance as it were, before it 

 enters into and indeed without its ever actually entering into the 

 composition of the living substance. On the other hand we must 

 equally admit that some of the waste substances are the direct 

 products of the katabolic changes of the living substance itself, 

 were actually once part of the living substance. Hence we ought 

 perhaps to distinguish the products of the activity of living matter 

 into waste products proper, the direct results of katabolic changes, 

 and into bye products which are the results of changes effected by 

 the living matter outside itself and which cannot therefore be con- 

 sidered as necessarily either anabolic or katabolic. 



Concerning the chemical characters of the living matter itself 

 we cannot at present make any very definite statement. We may 

 say that the proteid myosin, or rather the proteid antecedent or 

 antecedents of myosin, enter in some way into its structure, but 

 we are not justified in saying that the living substance consists only 

 of proteid matter in a peculiar condition. And indeed the per- 

 sistency with which some representative of fatty bodies, and some 

 representative of carbohydrates always appear in living tissue 

 would perhaps rather lead us to suppose that these equally with 

 proteid material were essential to its structure. Again though 

 the behaviour of the nucleus as contrasted with that of the cell 

 body leads us to suppose that the living substance of the former 

 is a different kind of living substance from that of the latter, we 

 do not know exactly in what the difference consists. The nucleus 

 as we have seen contains nudein which perhaps we may regard as 

 a largely modified proteid ; but a body which is remarkable for its 

 stability, for the difficulty with which it is changed by chemical 



