PANCREA TIC JUICE. 



367 



A temporary fistula should be made two or three hours after a meal, 

 and the fluid collected during the next two or three hours. The greater 

 number of such fistulse have been made on dogs. The fluid obtained is 

 clear like water, but of a slimy, syrupy consistency ; it becomes still 

 more viscid as it cools, and undergoes at C. a true coagulation, separat- 

 ing into a gelatinous and a fluid portion. Its specific gravity is about 

 1*030. It contains in suspension white corpuscles, which exhibit sluggish 

 amoeboid movements. It is alkaline in reaction, the alkalinity being 

 equal to 0*2-0 - 4 per cent, of NaHO, but the first few drops secreted may 

 be acid. The alkalinity is commonly said to be due to carbonates 

 and phosphates of sodium. The fluid is rich in proteid, froths on 

 shaking, and on heating to 75 C. coagulates to a solid white mass. 

 If kept warm for some time, its proteids become peptonised by the 

 trypsin present with them. On dropping into water a precipitate is 

 formed, which is soluble in dilute saline or acids. Alcohol gives 

 an abundant flocculent precipitate, mostly soluble in water, and con- 

 sisting of the proteid and enzymes. Leucine is present in traces, 

 but not tyrosine. Similar secretions have been obtained from many 

 other animals ; the pancreatic juice of herbivora (rabbit, ox, and sheep) 

 contains much less proteid than that of carnivora, but is in other 

 respects similar. 



The permanent secretion sets in at a variable period, from a 

 few hours to some days after the operation. It is very similar 

 to the temporary secretion, except in containing much less organic 

 matter, and in having in consequence a much lower specific gravity, 

 1-010-1-011. 



Quantitative chemical composition. The following table gives the 

 results of analyses of both temporary and permanent secretions of dog's 

 pancreatic juice by C. Schmidt : l 



Quoted fromMaly, Hermann's "Handbuch," Bd. v. (2), S. 189. 



