EFFECTS OF EXTRACTS. 



947 



is also due to contraction of the arterioles, is sufficiently shown by the 

 fact that if salt solution containing pituitary extract be passed through 

 the blood vessels of a frog, the entire nervous system of which has been 



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destroyed, the vessels markedly contract. This experiment conclusively 

 shows that the effect upon the arteries is a direct one, and in all pro- 

 bability the action upon the heart is also direct. 



