458 



STUDIES IN GENERAL PHYSIOLOGY 



TABLE II 

 ( F=110) 



When r=UO, ^ is about 375 for HC1 instead of 377. 

 The degree of dissociation is therefore only slightly different 

 from that when F 210. Nevertheless, the effect of the 

 acid is not doubled when the concentration is doubled, but 

 only increased about 50 per cent. Pronounced toxic effects 

 already show themselves when F=100. I need not again 

 point out how well the values agree with each other. 



I wish finally to give a series of experiments with 

 KHSO 4 andNaHSO 4 . One-tenth normal solutions of these 

 acids were used of which 10 c.c. were added to 100 c.c. of 

 a 0.7 per cent. NaCl solution. The amount of water 

 absorbed by the muscle is given in Table III. 



TABLE III 



( V = 110) 



The values are quantitatively almost equal to those of the 

 other acids, especially sulphuric acid. In these concentrations 

 the lesser degree of dissociation of the sulphuric acid when 

 compared with nitric or hydrochloric acid is clearly shown. 



If we sum up the results of all these experiments, we can 

 say that the acid effects (when V = 100 or 200} of HCl, 

 HNO 3 , JH 2 SO^ KHSO^, NaHSO, so far as these effects 

 are expressed in the absorption of water, or, more accurately, 

 in the increase in the weight of the muscle, are chiefly ion 



