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STUDIES IN GENERAL PHYSIOLOGY 



a larger number of organic acids, especially of the fatty series, 

 which I wish to report here. It is clear that these apparent 

 exceptions to the theory of electrolytic dissociation in the 

 case of the organic acids must yield material for understand- 

 ing the chemical changes which go on in living matter. 



The experiments were made as the previous ones. Five 

 or 10 c.c. of a one-tenth normal solution of the acids were 

 added to 100 c.c. of a NaCl solution. The gastrocnemius of 

 a frog was introduced into such a solution and its increase 

 in weight determined at certain intervals. 



The solutions which contained 10 c.c. of a one-tenth nor- 

 mal acid in 100 c.c. of a 0.7 per cent. NaCl solution in 

 which therefore the concentration V equaled 110 gave more 

 constant results than those solutions in which V equaled 210. 

 The following table gives the results of several series of 

 experiments with a series of acids when V equaled 110. The 

 Arabic figures give the increase in weight which each muscle 

 showed, expressed in per cent, of its original weight after 

 remaining for one hour in the solution. 



(F=110) 



We will now compare with this series the degree of dis- 

 sociation of these acids when V HO. 1 



i Calculated according to OSTWALD, " Ueber die AffinitatsgrOssen organischer 

 Sfturen," Abhandlungen der Sachsischen Gesellschaft der Wissenschaften, Vol. XV, 

 p. 89. 



