io6 



I'eicriuary Obstetrics 



aversion to niatiti^ with affected 



males soiuetinies show 

 females. 



Beebe and Ewing (Jour. Med. Re.search, Sept., 1906, do. A'et. 

 Jour., July, 1907) record the presence in the.se tumors of spi- 

 rochsete in one out of a .series of cases, but failed to connect their 

 presence with the cau.se of the malady. 



IT 



\ 



Fig. 12B. iNKECTiois Vknerk.\l GR.\Nri.OM.\ 01- Bitch. (C. A. White.) 



Later, Mettam ( Veterinary Journal, February, 1907) records 

 the discovery of an organism in this di-sease belonging to the 

 group of spirochaete, which he believes to be the .specific cause. 



Histologically, the tumors consist of large round or polyg- 

 onal cells, which multiply rapidly and push the contiguous 

 ti.ssues aside without their becoming involved in inflammatory 

 or other disease changes. 



Thedisea.se has been repeatedly transmitted experimentally by 

 inoculations in the genital muco.sa and other tissues. 



