LECTURES ON IMMUNITY 



pigs after direct injection l of this antibody in the blood of 

 these animals gave #=1.2. In this case the constant 

 const. 2 is nearly of the same magnitude for different dogs, 

 as one might expect (it is in three cases 0.15, 0.18, and 

 0.19). For the destruction of antibodies in the human 

 body, Madsen has found n = 2 in many cases. Of course 

 this formula is only an empirical one. Its physical mean- 

 ing is easily understood. The examples calculated by 

 Madsen show a very good agreement with the experiment. 

 As further instances may be cited the following figures 

 for the decomposition of typhoid agglutinin in the blood 

 of a passively immunised goat (according to Jorgensen 

 and Madsen) and in that pf a man who had suffered from 

 typhoid fever (according to Jorgensen). 2 x = concentration. 



= 8 X io- 6 . 



n = 1.2. 



const. 2 = 0.0302. 



1 So-called passive immunisation: "Active immunisation " is produced by 

 injection of the toxins or cells themselves, as is described above. 



2 Madsen : " Lecture Held at the Meeting of Brit. Med. Ass., Oxford, July, 

 1904," British Medical Journal, Sept. io, 1904. 



