VELOCITY OF REACTION. HETEROGENEOUS SYSTEMS 103 



INFLUENCE OF THE CONCENTRATION OF A POISON ON THE HAEMOLYSIS 



The blood often binds a certain quantity of the poison 

 added, so that under a certain concentration no haemolysis 

 occurs ; this was, e.g., the case with 10 c.c. of a suspension 

 containing 10 per cent of erythrocytes and less than 

 0.015 milligramme equivalent of caustic soda or ammonia. 

 The quantity bound is very strictly proportional to the 

 quantity of erythrocytes. 



An analogous case is seen in telanolysin, according to 

 the experiments of Madsen and Henderson-Smith. They 

 added different quantities, q, of telanolysin to 10 c.c. of 

 2 per cent suspension of erythrocytes from the horse and 

 determined the times which were necessary at 37 C. to 

 produce a certain degree of haemolysis. The results are 

 given below on p. 104. 



The time oo indicates that the quantity 0.25 telanolysis 

 does not give an appreciable haemolysis. Evidently the 

 product of the reacting quantity (^ 0.25) and the time of 

 action is constant. 



