206 



LECTURES ON IMMUNITY 



shows that normal rabbit-serum interferes with the agglutin- 

 ating, but not with the neurotoxic action of ricin. 1 



In the same manner as the nerve-poison of the ricin 

 behaves the haemolytic poison saponin, according to an 

 investigation of Madsen and Noguchi. 2 They investigated 

 its influence upon different quantities of blood-corpuscles. 

 The experiments were executed in the manner commonly 

 employed, so that to a given quantity (2 c.c. of a 2 per cent 

 solution) of poison (saponin) a certain quantity of antitoxin 

 (cholesterin) and so much physiological salt-solution was 

 added that the total quantity was 4 c.c. 



NEUTRALISATION OF 0.04 G. SAPONIN BY MEANS OF n c.c. OF 

 o. i n CHOLESTERIN 



Of the cholesterin solution 0.053 c.c. is equivalent to 0.04 g. 

 of saponin, or i c.c. to 0.76 g. K is given as K= 0.0166. 



1 Bashford: Journal of Hygiene, 4. 56 (1904). 



2 Madsen and Noguchi : Oversigt over d. k. danskc Vid-Sehtts Forh. y No. 6, 

 457 (1904). 



