NEUTRALISATION OF SIMPLE POISONS 



213 



mum and then subsequently rose, as the following figures 

 indicate : 



NEUTRALISATION OF WATER- MOCCASIN POISON (0.012 G.) WITH n. c.c. 



ANTITOXIN 



The measurements seem to indicate that the antitoxin 

 itself injured the guinea-pigs, in whom it was injected in 

 rather large quantities (10 c.c. in the last experiments). 

 The results recall those obtained in the neutralisation of 

 a base with an acid (cf. p. 173). The great loss of 

 antitoxin prevented the experiments from being carried 

 further. 



As will be seen in the next chapter, cobra-poison unites 

 with lecithin to form a compound, cobra-lecithid, of a very 

 high haemolytic action. Kyes 1 has isolated this cobra- 

 lecithid and thereafter prepared an antitoxin against it by 

 injections of this poison into the veins of a rabbit. As 

 normal serum of rabbit is itself a little antitoxic to cobra- 

 lecithid, but loses this property after heating for 30 

 minutes to 64 C., the immune-serum was heated during 

 30 minutes to 64 C., in which treatment the specific anti- 

 toxin remains unaltered. With these substances, cobra- 

 lecithid and its antitoxin, Kyes did some experiments on 



iKyes: I.e., p. 8. 



