214 



LECTURES ON IMMUNITY 



ox erythrocytes, the results of which are given in the 

 following table : 



NEUTRALISATION OF 0.4 c.c. SOLUTION OF COBRA-LECITHID WITH n c.c. OF ITS 



ANTITOXIN 



^=0.25 



The calculated figures, which agree very satisfactorily 

 with the observed ones, were obtained by means of the 

 equation found for the neutralisation of tetanolysin. The 

 high value of the constant shows that the combination is 

 far from complete ; in other words the neutralisation curve 

 differs widely from a straight line. 



Kyes and Sachs 1 stated that cholesterin has a strong 

 neutralising influence on cobra-lecithid as well as on cobra- 

 lysin. This action of cholesterin is even manifested against 

 the haemolytic power of tetanolysin and olive oil, but not 

 against that of staphylolysin or arachnolysin. 



Morgenroth 2 describes an experiment carried out by him 

 with a mixture of cobralysin containing a little more than 

 the double equivalent quantity of antivenin, in the presence 

 of lecithin. This mixture (in 10 c.c. of physiological salt- 

 solution) was brought into contact with rabbit erythrocytes 



1 Kyes and Sachs: Berl. klin. Wochenschrift, Nos. 2-4 (1903). 



2 Morgenroth : " Arbeiten aus dem pathologischen Institut zu Berlin," 

 1906, p. II. Cf. the experiments of Madsen and Walbum with ricin, against 

 which Morgenroth uses as an argument his experiment cited above. 



