ANAPHYLAXIS IN ITS RELATION TO DISEASE 



165 



But, as is shown in Fig. 8, antibodies still remain in considerable 

 amount, so that any factor which would now call a latent tubercular 

 focus into renewed activity, or the introduction of tuberculin from 

 without, would also call forth a prompt clinical reaction, either 



Mon.l 2 3,4 5 , 



Fio. 8 

 7 . 8 



. 33 



153 Months 



Threshold of 

 Sub&itaneov* 



'reaction 



Threshold of 



Cutaneous 



reaction 



Symptoms of Disease 

 Diagram illustrating benign course in a case of human tuberculosis. (Taken from v. Pirquet.) 



Threshold of Clinical evidence 



FIG. 9 



Days after appearance of eruption in measles 

 . . . . I I 1 I 8 . . . .. 



Death- 



Measles 



Miliarv Tuberculosis 



22 24 



Diagram illustrating the lighting up of a tubercular process (miliary tuberculosis) following 

 measles. (Taken from v. Pirquet.) 



general or local, as the case may be. Fig. 9 illustrates this very well, 

 and shows the mechanism which is called into action, when a miliary 

 tuberculosis follows an attack of measles, in a subject having a latent 

 (inactive) tubercular infection. 



