152 TETANUS 



even in a dose of a fraction of a milligram, it develops tetanus after a 

 period of incubation of a few days. Great care should be used in the 

 employment of vaccines and sera for fear of inoculation with 

 tetanus. The vaccine may carry the infection or it may be introduced 

 later through the vaccine lesion. Such an accident occurred at Camden, 

 New Jersey, in 1901, when several children vaccinated against small- 

 pox developed tetanus and died. A similar misfortune was reported 

 from India in 1902. Out of a group of 107 persons vaccinated against 

 plague, nineteen died of tetanus. In St. Louis, diphtheria antitoxin 

 was drawn from a horse which was apparently well, but which devel- 

 oped tetanus a fe wdays later. Some of the children treated for 

 diphtheria with this serum died of tetanus. 



