MICROCOCCUS IXTRACELLULARIS. 303 



Fifth, when obtained in pure culture by either of the 

 special procedures noted above, its cultivation may be 

 continued upon the same medium ; but growth will 

 usually not be observed if it is transplanted to ordi- 

 nary nutrient gelatin, agar-agar, bouillon, or potato ; 

 should it grow under these circumstances its develop- 

 ment will be very feeble. (Is this the case with com- 

 mon pus-producers?) 



Sixth, it has no pathogenic properties for animals, 

 while several of the pyogenic cocci, notably micrococcus 

 aureus and streptococcus pyogenes, are usually capable 

 of exciting pathological conditions. (This is less com- 

 monly true of streptococcus pyogenes than of micrococcus 

 aureus.) 



MICROCOCCUS INTRACELLULARIS (WEICHSELBUAlf), 

 MIGULA, 1900. 



Synonyms : Diplococcus intracellularis meningitidis, Weichselbaum, 

 1887; Streptococcus iiitracellularis (Weichselbaum), Lehmauu and 

 Neumann, 1896. 



Of the several organisms mentioned that might be 

 mistaken for the gonococcus, no one of them is as sug- 

 gestive and none, per se, so important as that concerned 

 in the causation of epidemic cerebrospinal meningitis. 



This organism, described by Weichselbaum in 1887 

 under the name "diplococcus intracellularis meningi- 

 tidis," was found by him in the exudations of the brain and 

 spinal cord in six cases of acute cerebrospinal meningitis. 



As its name implies, it is a diplococcus, practically 

 always seen within the bodies of pus-cells (polymorpho- 

 nuclear leucocytes) in the exudations characteristic of 

 this disease. It is not seen within the other cells of the 

 morbid process. It slains readily with any of the ordi- 



