386 BACTERIOLOGY. 



Growth in bouillon is characterized by a tough, slimy 

 sediment, and at times by more or less of pellicle-forma- 

 tion. Pellicle-formation is encouraged by the addition 

 of glycerin. The bouillon is not uniformly clouded by 

 the growth. 



In milk, it causes an alkaline reaction, solution of 

 casein, but no coagulation. 



On potato, it grows slowly as a dull yellowish-white 

 dry membrane. 



Bovines, sheep, and guinea-pigs are susceptible to in- 

 oculation ; rabbits, dogs, cats, horses, and asses are not. 



When pure cultures are injected into either the circu- 

 lation or the peritoneal cavity of guinea-pigs, death en- 

 sues in from nine to twenty days. The autopsy reveals 

 diifuse pseudotuberculosis of the omentum. "Within 

 the pseudotubercles the organism is seen as long, 

 branching threads, often matted together as a true 

 mycelium. 



By subcutaneous inoculation only the neighboring 

 lymph -glands are affected. 



The disease farcin des boeufs is said to be more com- 

 mon in Guadeloupe than elsewhere. 



ACTIXOMYCES EPPINGERI. This organism was dis- 

 covered by Eppinger in an abscess of the brain. He 

 regarded it as a cladothrix, and gave to it the designa- 

 tion cladothrix asteroides. It grows well in pure cult- 

 ure under artificial conditions, and is pathogenic for 

 animals. In the case studied by Eppinger the organ- 

 ism was present not only in the abscess, but also in the 

 meninges of the brain and cord and in the bronchial 

 and supraclavicular lymph-glands. There is no doubt 

 of its causal relation to the conditions. 



In pure culture it grows well on ordinary media. It 



