BACILLUS CHAUVEL 555 



may be detected. (How does this compare with bacte- 

 rium anthracisf) By successive inoculations of suscepti- 

 ble animals with serous fluid from the site of inoculation 

 of the dead animal the disease may be reproduced. 



Cattle, sheep, goats, guinea-pigs, and mice are sus- 

 ceptible to infection with this organism, and present the 

 conditions above described ; whereas horses, asses, and 

 white rats present only local swelling at the site of inoc- 

 ulation. Swine, dogs, cats, rabbits, ducks, chickens, and 

 pigeons are, as a rule, naturally immune from the disease. 



Though closely simulating the bacillus of malignant 

 oedema in many of its peculiarities, this organism can, 

 nevertheless, be readily distinguished from it. It is 

 smaller ; it does not develop into long threads in the 

 tissues ; it is more actively motile, and forms spores 

 more readily in the tissues of the animal than does the 

 bacillus of malignant oedema. In their relation to ani- 

 mals they also differ ; for instance, cattle, while con- 

 spicuously susceptible to symptomatic anthrax, are prac- 

 tically immune from malignant oedema ; and while swine, 

 dogs, rabbits, chickens, and pigeons are readily infected 

 with malignant oedema, they are not, as a rule, suscepti- 

 ble to symptomatic anthrax Horses are affected only 

 locally, and not seriously, by the bacillus of symptomatic 

 anthrax ; but they are conspicuously susceptible to both 

 artificial inoculation and natural infection by the bacil- 

 lus of malignant oedema. 



The distribution of the two organisms over the earth's 

 surface is also quite different. The oedema bacillus is 

 present in almost all soils, while the bacillus of symp- 

 tomatic anthrax appears to be confined to certain locali- 

 ties, especially places over which infected herds have 

 been pastured. 



