BLOOD. 299 



blood-coi'puscles differed but little from their normal standard, 

 but the quantity of fibrin varied considerablyj although the in- 

 crease above the normal mean was only small. It is worthy 

 of remark that the quantity of fibrin appears to increase, al- 

 though only slightly, by repeated bleeding; a cii'cumstance which, 

 according to Andral and Gavarret, characterizes the phlogoses. 



This may be due to the inflammatory state of the skin in 

 this disease, although we do not perceive a similar occurrence 

 in typhoid fever, in which the mucous surface of the intestine 

 is in a somewhat similar state. 



Their analyses gave the following results : 



Venesection. Water. Fibrin. Blood-corpuscles. Residue of serum. 



{1 771-5 4-4 120-6 1035 



2 780-8 2-9 110-2 1061 



3 820-2 3-2 94-6 82-0 



ri 791-3 3-0 114-3 91-4 



J 2 803-9 3-2 92-6 100-3 



" i 3 811-8 3-0 88-4 96-8 



[^4 817-3 3-3 87-0 92-4 



3j ri 781-4 2-6 127-9 88-1 



" l2 792-0 3-5 124-4 80-1 



^^^ ri 796-0 4-1 126-5 76-4 



" L2 792-7 2-0 124-9 80-4 



5th „ 1 805-0 2-9 98-8 92-3 



The residue of the serum contained on an average 7*0^ of 

 inorganic constituents. 



In the first case, the first bleeding was ordered at the com- 

 mencement of the disease, during the febrile period ; the second 

 at the commencement, and the third at abovit the middle of 

 the eruptive stage. In the second case, the first bleeding was 

 ordered some days before the appearance of the disease ; the 

 second dm-ing the fever; the third on the third day of the 

 eruption, and the fourth on the sixteenth day of the eruption. 

 In the third case, the fii"st bleeding was ordered at the com- 

 mencement of the eruption; the second during the suppurative 

 stage. In the fourth case, both venesections were prescribed 

 during the height of the eruption. In the fifth case the pus- 

 tules were filled with blood (variole hemorragique :) the bleed- 

 ing was ordered when the eruption was at its height. 



The analyses of blood in varioloid gave the following results : 



