332 CIRCULATING FLUIDS: 



In another case of a similar nature, the fat amounted to 

 4*176, consisting of: 



Serolin . . . , 0-128 



Phosphorized fat . . 1*159 



Cholesterin . . . 0*556 



Saponified fat . . . 2-333 



In adddition to the large amount of fat in the blood in these 

 cases, Becquerel and Rodier observed that the serum was always 

 tinged with bile-pigment.] 



IV. FAT IN THE BLOOD : PIARH^MIA. 



It is well known that free fat in the form of globules is not 

 ordinarily seen in healthy human blood. The greater part 

 exists in a saponified state, with the excej)tion of cholesterin 

 and serolin, which do not saponify with potash. As, however, 

 the chyle contains a large quantity of free fat soon after the act 

 of digestion, Ave must conclude that during the process of me- 

 tamorphosis of the blood the greater part becomes converted 

 into fatty acids. In certain pathological states of those organs 

 which play an active part in the metamorphosis of the blood, 

 and whose cells contain a considerable quantity of fat, as the 

 liver and kidneys, and during inflammatory affections of the 

 peritoneum and of the lungs, so large a quantity of both free 

 and combined fat is sometimes found in the blood, that the 

 serum appears turbid, opaque, and even milky. 



Marcet found the serum milky in diabetes. Trail in hepatitis, 

 Zanarelli in pneumonia, Christison in dropsy, icterus, and ne- 

 phritis ; moreover, in cholera the blood has been found to be 

 very abundant in fat. 



It is hardly necessary to observe that if in such cases the 

 serum appear turbid, whey-like, or milky, fat-globules will be 

 perceptible under the microscope. 



Christison and Lecanu^ have found that this, like most of the 

 animal fats, consists of olein, margarin, and stearin : there is 

 little doubt but that fatty acids are also present; in fact, Lassaigne 

 detected a fat of this nature in the blood, similar to the fatty mat- 

 ter of the brain. 



Zanarelli^ found the blood of a man with pneumonia similar 



' Etudes chimiques, p. 116. 



' Journal de Chimic Medic, vol. 2, p. 551. 



