BLOOD. 



345 



They remark that the changes which the blood of these 

 animals undergoes in disease, precisely correspond with those 

 of human blood in similar disorders. Thus, in inflammatory 

 diseases, there is always an excess of fibrin, and they observe 

 that in those animals in which the normal mean amount is 

 highest, the fibrin is increased in the greatest proportion; thus 

 in the blood of a cow with inflammation of the respiratory or- 

 gans, the fibrin rose to 13-0, the normal amount in that animal 

 being 3"8. In dogs that were reduced to a very anaemic con- 

 dition, the blood-corpuscles fell from the normal mean 148, to 

 104, and even down to 83. 



Theii* attention was, however, principally directed to the 

 watery cachexia, or rot in sheep. The most prominent phe- 

 nomena of the disease were extreme debility, paleness of the 

 mucous membranes, and very frequently serous infiltration of 

 the conjunctiva, and of the cellular tissue of the integument of 

 the feet. No albumen was detected in the urine. From 

 27 analyses made with the blood of 11 sheep, they conclude 

 that the amount of fibrin is slightly aSected, but that the blood- 

 corpuscles are excessively diminished ; from 78, their normal 

 average, they fall to 40, 25, and even 14. The solid residue 

 of the serum is diminished, (a point in which this disease diff'ers 

 from chlorosis in the human subject,) and the water is consi- 

 derably increased. 



The deficiency in the amount of blood-corpuscles appeared 

 to vaiy with the progressing weakness of the animal. By 

 proper food, and due attention to atmospheric influences, the 

 corpuscles were observed to increase; in one instance they rose 

 from 49 to 64. 



From 14 analyses of the blood, in which this affection was 

 associated with inflammatory disorders, it appeared that the 



