ARTIFICIAL PRODUCTION OF TUBERCLE. 17 



should almost question the accuracy of my own observations, whether I may 

 not have overlooked one or two enlarged glands in these instances. 



The lungs have heen affected in fifty-nine out of the sixty-four. In one, 

 they were unchanged, when the spleen alone was affected ; in one, when the 

 liver, spleen, intestines, and mesentery were affected ; in one, when the liver 

 and spleen suffered ; in another case, the affection was doubtful in its nature. 



The bronchial glands escaped only eight times out of the sixty -four; 

 twice only when there was any considerable lung-affection present. 



The spleen has been affected fifty -nine times, only escaping five times out 

 of the whole group. 



The liver has been affected fifty-one times. In nine, the character of the 

 affection was considered doubtful, consisting only of cheesy spots, which in 

 some cases appeared to be due to psorosperms, and where no other distinct 

 affection could be discovered. In four, it was altogether absent. 



Of the omentum my notes are less perfect. It was affected twenty-five 

 times. The condition was not stated in twelve cases. 



The intestines were affected in twelve cases ; not examined in twenty-two. 

 In the rest, though examined, no affection was found. 



The mesenteric glands were affected forty-five times out of the sixty-four. 



In two cases granulations, having all the character of grey tubercle, were 

 found sparsely scattered in the kidney. Microscopic examination showed that 

 these growths corresponded with the grey tubercular granulations found in 

 this organ in man. They consisted of small cells and nuclei imbedded in 

 a fibrous matrix, and they were situated in the intertubular tissues. 



In two cases the uterus was found in a state of catarrhal inflammation, 

 and in one of these its interior was found filled with a cheesy matter, much 

 resembling in this respect a drawing of Carswell's of tubercle of the uterus.^ 

 Microscopic examination showed small granulations having the ordinary 

 tubercular character in the submucous and intertubular tissues. The 

 glands presented the ordinary appearances of catarrhal change, having their 

 epithelium swollen and granular. In the case last mentioned the retro- 

 peritoneal and lumbar lymphatics were enlarged, indurated, and cheesy, 

 thus presenting appearances similar to those before described as occurring 

 in other parts. 



In one or two cases opaque spots were found in the cornea. In one of 

 these, which Mr. Vernon had the kindness to examine for me, there were 

 seen cells of new formation imbedded among the corneal fibres and under- 

 going fatty degeneration. Neither in this case nor in many others which 



1 Loc. cit. Tubercle, PL II. figs. 1, 2. 

 I> 



