254 IMPORTANT VARIETIES OF FISSION-FUNGI. 



recently also in Hungary, Bosnia, etc. Th. Smith (C. B. 

 ix, 253) describes the following forms : 



Acute Form. — Hemorrhagic septicemia ; hemorrhages especially 

 observed in the lungs, kidneys, and serous membranes (stomach, 

 intestine). Marked splenic tumor. Death in a few days. 



Chronic Form. — Animal emaciated, gait tottering. Larger and 

 smaller necrotic areas (ulcers) on lips, palate, tongue. Mucous lining 

 of stomach very red, in places showing ecchymoses. Necrotic areas 

 (sometimes dry, nodular infiltration, sometimes broken-down ulcers) 

 are sometimes seen in the small intestine and rectum, and more often 

 in the cecum and colon. The lungs are not much changed, but there 

 may be some atelectasis or bronchopneumonia. The kidneys are 

 almost always diseased, albumin and casts appearing in the urine. 

 There is a splenic tumor, usually necrosis in the liver. Death in two 

 to four weeks. 



Animal Experiments. — Guinea-pigs, rabbits, and pi- 

 geons are susceptible. 



Differential Diagnosis. — 



American Swine-Plague. German Schweineseuche. 



(Swine-pest = Hog cholera. ) (Loffier and Schiitz. See p. 209. ) 



Bacterium cholerae suum. L. and Bacterium suicida Migula. 



N. 



Very actively motile. Non-motile. 



Ferments grape-sugar. Does not ferment grape-sugar. 



Luxuriant growth on potato. Little or no growth on potato. 



•Rather luxuriant growth on agar, Slow growth, on agar, coherent 



very friable. (Karlinski). 



No changes at the point of infec- Marked changes at the point of 



tion. infection. 

 Multiple areas of coagulation Liver often the seat of fatty de- 

 necrosis in the liver. generation. 

 Few bacteria in blood. Abundant bacteria in blood of 



the heart and large vessels. 



Very few bacteria at the site of Abundant bacteria in the inflam- 



inoculation. matory edema at the point of 



inoculation. 



Pigeons very susceptible, guinea- Guinea-pigs very susceptible, 



pigs less so. pigeons less so. 



The following are closely related to the Bacterium cholerae 

 suum, and differ somewhat more from the Bact. coli on 

 account of the absence of some biologic (not morphologic) 

 peculiarity. 



Bacillus of Intestinal Diphtheria Ribbert (Deut. med. Woch- 

 enschr., 1887, No. 8, 141). — This peritrichous organism is indis- 

 tinguishable morphologically from the Bact. coli, yet the culture in 

 our institute (cultivated for eight years upon non-saccharine nutrient 



