BACTERIUM ERYSIPELATOUS SUUM. 303 



lation is made in gelatin from the blood, according to 

 Lorenz, the branches are sometimes almost entirely absent 

 from the primary cultures, and, instead, only nodules and 

 globules are seen in the stab. The principal difference lies 

 in the gelatin plate colonies, which were described by 

 Loffler as minute, distinctly visible growths, with a few 

 irregular radiations (like bone corpuscles), and which 

 were found by us to be constantly somewhat between 31, 

 vi, e, and 31, vn, on an average. Compare Losener, A. 

 G. A. xu, 448. There is intense production of H 2 S, and 

 little of indol. Some acid is formed from grape-sugar. 



Regarding a rather considerable resistance to pickling 

 and smoking, consult Petri (A. G. A. vi, 266). 



It causes an important disease of swine, young animals 

 of the choicer varieties being especially affected. Older 

 animals, and also younger ones of ordinary breeds, 

 are more or less immune. Upon section the animals 

 show, besides a patchy or diffuse redness of the skin, 

 which is often very marked, also subcutaneous edema, 

 redness of the pharynx and of the gastric and intestinal 

 mucosa, swelling of the mesenteric glands and spleen, 

 parenchymatous nephritis, hemorrhages in the kidneys, 

 and red spots in the lungs. Consult Graffunder, Berl. 

 tierarztl. Wochenschrift, 1896, No. 2. 



The organism is not pathogenic for man, also the flesh 

 of swine affected with erysipelas is harmless. 



Mice sicken and die after feeding, and more rapidly 

 after inoculation; also rabbits usually succumb to inocu- 

 lation. 



The differential diagnosis from other diseases of swine 

 is easy, from the characteristic form of the individuals 

 and from the cultures of the organism. It must not be 

 forgotten that redness of the skin in patches occurs in 

 many diseases of swine, as in Loffler-Schutz' s swine plague 

 (see p. 254). 



Protective Inoculation. — Animals may be actively 

 immunized with attenuated bacteria (Pasteur), with de- 

 vitalized bacteria, with body juices (Emmerich) and blood- 

 serum (Lorenz, C. B. xix, 168). 



According to Voges and Schiitz (Z. H. xxviii, 38), 

 no method has stood practical tests. The serum of ac- 



