470 DISEASES WITH UNCERTAIN CAUSES. 



eosin solution (in 70% alcohol) after three hours at incu- 

 bator temperature. Only from the sixth day of the disease 

 on, are the organisms found in preparations, which does 

 not bespeak an etiologic significance for them. Still, the 

 discoverers consider this organism, which does not stain by 

 Gram's method, and cannot be cultivated (only upon 

 blood-bouillon many times a slight growth appears), to be 

 the cause of measles. 



Recently Czajkowski (C. B. xvm, 517) has found sim- 

 ilar organisms in the blood, which he has portrayed and 

 cultivated upon glycerin-agar, but especially upon blood- 

 glycerin-agar. The growth is delicate, scanty, and like 

 dewdrops. The organism is pathogenic for mice. It is 

 motile and is not stained by Gram's method. 



Mouth and Foot Disease. 



In opposition to numerous defective investigations which 

 have recognized the cause of this disease in most variable 

 sized and sometimes easily cultivated fission-fungi (com- 

 pare Stutzer and Hartleb, A. H., 1897, 372), Loffler and 

 Frosch have determined that the cause of the foot and 

 mouth disease is indeed present in the contents of the 

 mouth and foot vesicles, but that it is so minute that 

 it passes through dense bacterial filters and is invisible 

 with the best microscopes. Only after repeated filtration 

 through the densest filters does the lymph lose its infec- 

 tious properties (C. B. xxin, 371). 



Myxoma Disease. 



The cause is so far unrecognizable. The disease occurred 

 spontaneously in Sanarelli's rabbits in Montevideo. It 

 manifests itself in conjunctival catarrh, leonine swelling of 

 mouth and nose, inflammatory swelling of the urinary and 

 genital organs and buttocks, especially in hyperplastic 

 changes at the places where the skin and mucous mem- 

 branes join. Also, myxomatous or gelatinous subcutane- 

 ous swellings which are very vascular are found in various 

 parts of the body. In most animals dying from the sub- 

 acute disease the postmortem reveals hypertrophy of the 

 lymph glands, orchitis, and swelling of the spleen. The 



