284 PATHOGENIC BACTERIA IN MILK 



Board, summarised his interpretation of these facts in the follow- 

 ing words : — 



"By Dr Klein's researches, together with the evidence as to 

 scarlatina collected by Dr Power and reported by me last year, we 

 are now in a position to state as follows concerning the disease 

 producible by this micrococcus in bovine animals and in man : — 



" (i) The disease in man and in the cow alike is characterised 

 by closely similar anatomical features. 



" (2) From the diseased tissues and organs of man and cow 

 alike the same micrococcus can be separated, and artificial sub- 

 cultures be made from it. 



"(3) These subcultures, no matter whether established from 

 man or cow, have the property, when inoculated into calves, of 

 producing in them every manifestation of the Hendon disease, 

 except sores on the teats and udders, no doubt for the reason that 

 the milk apparatus is not yet developed in calves. 



" (4) But — and this I learn from Dr Klein's later observations 

 while this report is in preparation — the subcultures made from 

 human scarlatina and inoculated into recently calved cows can 

 produce in those cows, along with other manifestations of the 

 Hendon disease, the characteristic ulcers on the teats — ulcers 

 identical in character with those observed at the Hendon farm. 



" (5) The subcultures, established either from the human or the 

 cow disease, have an identical property of producing, in various 

 rodents, a disease similar in its pathological manifestations to the 

 Hendon disease of cows and to scarlatina in the human subject. 



" (6) Calves fed on subcultures, established from human scarla- 

 tina, obtain the Hendon disease. 



" (7) Children fed on milk from cows suffering under the Hendon 

 disease obtain scarlatina. 



" The above combine, I think, to form a mass of evidence to 

 show that the Hendon disease is a form, occurring in the cow, of 

 the very disease that we call scarlatina when it occurs in the human 

 subject. 



" He [Dr Klein] takes such animals and inoculates them sub- 

 cutaneously at the root of the ear with the material of scarlatina. 

 Sometimes he has derived the material direct from the human 

 subject, sometimes after it has passed through the system of a 

 calf. From whichever source the material may be derived, itsj 

 inoculation results in ulcers on the teats of the cows. He finds' 

 these ulcers to be among the very earliest evidences of disease 

 in the animal. They occur indifferently whether the cow is 



