Pathogenesis 



spores or bacilli with a heavy platinum wire, the end of which 

 is flattened, pointed, and perforated. An animal inoculated 

 in this way dies, according to the species, in from twenty 

 four hours to three days, suffering from weakness, fever, 

 loss of appetite, and a bloody discharge from nose and 

 bowels. There is much subcutaneous gelatinous edema 

 near the inoculation wound. The abdominal viscera are 

 injected and congested. The spleen is enlarged, dark in 

 color, and of mushy consistence. The liver is also some- 

 what enlarged. The lungs are usually slightly congested. 



Fig. 164. Anthrax bacilli in glomeruli of kidney. 



When organs which present no appreciable changes to the 

 naked eye are subjected to a microscopic examination, the 

 appropriate staining methods show the capillary and 

 lymphatic systems to be almost universally occupied by 

 bacilli, which extend throughout their meshworks in long 

 threads. Most beautiful bacillary threads can be found in 

 the glomeruli of the kidney and in the minute capillaries 

 of the intestinal villi. In the larger vessels, where the 

 blood-stream is rapid, no opportunity is afforded for the 

 formation of the' threads, and the bacteria are relatively 



