fi20 Mr. W. Brande's Additional Observations 



violence of the operation, he was so fortunate as to void the 

 calculus with his urine; it weighed eight grains. On the 28th 

 he again suffered pain in the region of the kidneys, and voided 

 much sand, composed of uric acid, with ammoniaco-magnesian 

 phosphate. He now took three half pints of soda water daily, 

 which materially increased the proportion of the triple phos- 

 phate, while that of uric acid was considerably diminished. 

 Ten drops of muriatic acid were then taken three times 

 a day in water. The red sand now began to re-appear, 

 and on the 4th of February, he voided a very small uric 

 calculus. The urine made after dinner contained more or 

 less mucus streaked with blood, a symptom which was 

 much aggravated by a slight excess in wine. On the 6th, he 

 left London, and employed no medicine until the 12th, when 

 he returned in consequence of having voided a large quantity 

 of the white sand. 



Having observed the efficacy of carbonic acid in preventing 

 the deposition of the phosphates, and having found it less liable 

 than any other acid to induce a return of the uric gravel and 

 calculi, I now directed him to take half a pint of water highly 

 impregnated with fixed air, four or five times a day, and to 

 drink cyder instead of wine. On the 18th of February, his 

 urine was less turbid than it had been for some months before, 

 and on the 20th of March, having continued the use of car- 

 bonic acid, he had no remaining symptoms.* 



• I have several times examined the urine, with a view to ascertain whether any of 

 the acids which were exhibited, could be detected in that secretion ; but the results of 

 such experiments are so much interfered with by the very compound nature of the 

 urine, that I have not hitherto been able to draw any satisfactory conclusions respect- 

 ing them. 



