124 MOSQUITOES 



part of 1900 were extremely sugg-estive in their results. 

 In the course of the investig-ations, both Drs. Carroll and 

 Lazear were attacked by the disease. Dr. Carroll recov- 

 ered, but Dr. Lazear died — another of the long list of 

 martyrs who have suffered in the cause of scientific 

 research. In this preliminary work, which Dr. Keed 

 reported upon at the twenty-eig-htli annual meeting of 

 the American Public Health Association, Indianapolis, 

 Ind., October 23, 1900, it was shown that eleven non- 

 immune individuals had been inoculated by the bites of 

 the species then known as Cidexfasdatas,\i\n.Q\\ had previ- 

 ously fed upon blood of patients sick with yellow fever. 

 Dr. Reed was able to report two positive results in which 

 an attack of yellow fever followed the bite of a mosquito 

 within the usual period of incubation of the disease. In 

 one of the cases all other sources of infection could posi- 

 tively be excluded. The results of this preliminary work 

 were summed up in two conclusions : 1. Bac'dlas icte- 

 Toides Sanarelli stands in no causative relation to yellow 

 fever, but when present should be considered as a second- 

 ary invader in this disease. 2. The mosquito serves as 

 the intermediate host for the parasite of yelloAv fever. 



The announcements made in this preliminary note ex- 

 cited much attention. The scientific standing of the in- 

 vestigators, as well as the positive result announced in 

 one of the cases, made the tlieor}^ at once one of serious 

 importance. Medical men, however, were inclined to wait 

 for further developments before expressing an opinion. 

 Their point of view was perhaps well summed up by the 

 British Medical Journal, which stated that although the 



