BLACK-LEG 77 



vaccine into cattle immunises them sufficiently and 

 lastingly. This method is conducted in the same 

 way as that of Arloing, Cornevin, and Thomas's. 

 By either method the immunity established is believed 

 to last for eighteen months. 



3. Black-leg aggressin. A germ-free product, pre- 

 pared from the tissue juices of calves previously 

 inoculated with the black-leg organism. This confers 

 a rapid and lasting immunity. Dose is 5 c.c, given 

 subcutaneously. 



4. Black -leg filtrate, also known as artificial 

 aggressins. This is a germ-free cultural product, the 

 dose and method of application being the same as for 

 the aggressins. 



It has been conclusively proved that the immunity 

 following both the aggressins and filtrate, which in 

 themselves are complex and not thoroughly under- 

 stood bacterial products, is strong, lasting, and satis- 

 factory. 



5. An immune serum has been prepared from 

 hyperimmunised animals, the animals used being 

 horses or cattle. The use of this serum is becoming 

 extremely popular as a curative for the disease, as 

 results show that this product is quite efficacious in 

 the treatment of infected animals. 



Swine Erysipelas.— Swine erysipelas is an acute 

 septicemic infectious disease of young pigs, caused by 

 a very fine rod-shaped bacterium, the Bacillus ery- 

 sipelatis suis. 



