SWINE EEYSIPELAS 79 



2. Serum simultaneous method (method of Lorenz 

 and Leclainche). 



The serum is obtained from hyperimmunised 

 animals, and this is used in conjunction with virulent 

 cultures. The advantage of this method over Pasteur's 

 consists in the development of the passive immunity 

 immediately after the serum is injected. This method 

 is also attended with some of the dangerous results 

 seen in Pasteur's method. 



Dose : 1 c.c. of a bouillon culture and 9 c.c. of 

 immune serum are injected simultaneously. The 

 serum and culture are well mixed before injection. 

 The injections are made on the inner surface of the 

 thigh. 



3. Passive immunity is established, and lasts for 

 sixteen to eighteen days, by the use of immune serum. 

 This method has the advantage in cases where the 

 infection has occurred, and in animals open to infec- 

 tion, as the necessary immunity is rapidly established. 

 Serum is also used in treatment of the disease, with 

 considerable success if given at the onset. 



Doses : 10 to 30 c.c. given subcutaneously for 

 treatment, and repeated every six hours. For passive 

 immunity, 10 to 15 c.c. is sufficient. 



Hemorrhag'ic Septicemia or Pasteureilosis. — 



Under the collective name of '* hemorrhagic septi- 

 cemia " are included all those diseases which are pro- 

 duced by varieties of the Bacillus hipolaris se2)ticus, 

 and in which the acute cases are characterised by 



