90 VACCINE AND SERUM THERAPY 



anaphylotoxins of Friedberger, or a sequel to a 

 specific infection. It is principally characterised by 

 extensive oedematous infiltrations of the subcutaneous 

 connective tissue and by hemorrhages in the swel- 

 lings, as well as in the mucous membranes and in the 

 internal organs. 



Prophylaxis and Treatment. — No attempt at im- 

 munisation against this disease has been made. 



In treatment various authors, on the presumption 

 that this disease was a bacterial infection or sequel to 

 a bacterial infection, due to the cocci group of 

 organisms, have used antistreptococci serum, and, 

 according to reports, with favourable results. How- 

 ever, Cadeat obtained equally good results with normal 

 blood serum. Treatment of this disease by the use of 

 vaccines has not been attempted. 



Strangles.— Strangles is an acute contagious in- 

 fectious disease of horses, in the course of which 

 catarrhal symptoms of the upper air passages 

 develop in association with suppurative inflammation 

 in the adjoining lymph glands, and sometimes in a 

 generalised form in more distant lymph glands. 



Etiology. — The Streptococcus equi. Horses when 

 recovered from this disease are immune to subsequent 

 natural infection. This immunity lasts for several 

 years. 



Immunisation and Scrum Treatment. — As in all 

 other streptococci infections, serum treatment is of 

 very little use as a curative ; however, it is very useful 



