108 VACCINE AND SERUM THERAPY 



formation of local tumours resembling fibromata, and 

 occasionally in the formation of metastases in the 

 internal organs. Abscesses often form in these 

 tumours, which burst, and a running fistula remains, 

 or there may be several small fistulse opening on 

 different parts of the tumour. 



Etiology. — The Botryomyces equi, or Micrococcus 

 ascqformans. 



Lesions of this disease occur frequently on the 

 shoulders of horses, in the mammary gland and the 

 spermatic cord after castration. 



Treatment. — I have successfully treated three cases 

 of this disease with autogenous vaccine. 



1. A driving horse, with a large tumour at base of 

 neck, which surrounded the jugular vein. On account 

 of its involving the vein, I refrained from removing 

 the tumour by surgical measures. Instead I opened 

 into the pus cavity, and obtained a swab, from which 

 an autogenous vaccine was prepared. The vaccine 

 was employed at intervals of eight to ten days, each 

 dose containing an increased number of cocci. The 

 initial dose consisted of 80 million cocci, each subse- 

 quent dose increased by one-fourth the number of the 

 preceding dose. Altogether twenty injections were 

 made, by the end of which the tumour had dis- 

 appeared ; all that remained was a thickened condition 

 of the overlying skin. 



2. Large tumour in right half of mammary gland 

 of a thoroughbred mare. This tumour contained four 

 fistulfe, from which a thick sticky pus was flowing. 



