112 VACCINE AND SERUM THERAPY 



commonly by the bull, but may also be^ carried by 

 litter contaminated with the discharge from the 

 external genitals of an infected animal. 



Treatment. — When the disease is confined to the 

 vulva and vagina, it yields to local medicinal treat- 

 ment ; but it commonly spreads to the cervix, uterus, 

 Eallopian tubes, and even the ovaries, establishing 

 a chronic inflammation in these organs. Under these 

 circumstances it becomes a serious affection, especi- 

 ally when the Fallopian tubes and ovaries are in- 

 volved, as sterility is always the sequel. In the 

 above conditions an autogenous vaccine should be 

 prepared, the causal organism being procured by 

 taking a swab of the uterine discharge. 



In chronic salpingitis, which is very often associated 

 with cystic ovaries, very favourable results follow 

 treatment with an autogenous vaccine. As the cystic 

 condition of ovaries is secondary to the endometritis 

 or salpingitis, and often intimately associated with 

 these conditions, disappearance of the ovarian cysts 

 foUow^s the disappearance of the primary lesions in 

 the uterus or Fallopian tubes. In the many cases of 

 nymphomania seen in mares and cows, the primary 

 cause is either an endometritis, followed by sal^Ding- 

 itis, or either condition may act separately as an 

 excitant to the production of ovarian cysts, which 

 give rise to the condition of nymphomania. By 

 treatment of the primary lesions and effecting their 

 cure, in the great majority of cases the ovarian cysts 

 will disappear, and likewise the objective symptoms 



