BARIUM 151 



Calcium phosphate, according to the foregoing, are rickets, 

 osteomalacia, delayed union in fractures ; also anaemia, 

 malnutrition, and weakness in young animals. Here the 

 drug should be given with iron. 



Administration. — Precipitated calcium phosphate may 

 be given on the food, but is more readily absorbed if it is 

 administered in the syrup of calcium lactophosphate. 



Calx Chlorata. (See Chlorine, p. 222.) 



Barium. 



(Barium is not used in the metallic state.) 



Baeii Chloridum. Barium Chloride. BaClg. (Non-official.) 



Derivation. — Native barium sulphate is fused with 

 charcoal. The resulting sulphide is treated with hydro- 

 chloric acid. BaSO, + 2C = BaS + 2 CO,. BaS + 2 HCl 

 = BaCl, + H,S. 



Properties. — Occurs in colorless, glistening rhombic 

 plates ; taste bitter and disagreable ; permanent in dry air ; 

 soluble in 2.5 parts of cold water ; reaction neutral. 



Dose. — H., 3 i.-ii. (4.-8.); intertracheally, gr.vii.-xv. (.5-1.). 



Action Internal. — Barium chloride is an intense irritant 

 if swallowed in considerable amount and in insufficient 

 dilution. Large medicinal doses stimulate the muscular 

 coat of the bowels and cause increased peristalsis and 

 purging. Evacuations from the bowels follow in horses, 15 

 to 45 minutes after the salt is given in drench ; in one to two 

 hours after administration to these animals in ball. Intra- 

 venous injection is unsafe, and subcutaneous application 

 may occasion abscess. The drug resembles physostigmine 

 in its action on the intestines. 



Heart and Blood Vessels. — Barium chloride makes the ven- 

 tricular contractions of the heart stronger and slower. The 

 salt acts entirely on the heart muscle and does not influence 

 the vagi. Lethal doses are followed by slower and slower 

 ventricular contractions, succeeded by peristalsis of the 



