PHOSPHORUS PREPARATIONS 219 



PREPARATIONS. 



Oleum Phosphor atum. Phosphorated Oil. (U. S. & B. P.) 



Phosphorus, 1 gm.; expressed oil of almond and ether, of each a 

 sufficient quantity to make 100 gm. (U. S. P. ) 



Properties.— A clear, yellowish liquid, having the odor of phosphorus 

 and ether. The ether in this preparation evaporates in time and the 

 strength is proportionately, and perhaps dangerously, increased. 



Dose.— H., 3ii.-iii. (8.-12.); D., mi. -v. (.06-.3). 



Spiritus Phosphori. Spirit of Phosphorus. (U. S. P.) 

 Phosphorus, 1.2 gm.; absolute alcohol, a sufficient quantity to make 

 1000 Cc. Teaspoonful = ^V o^ a grain. 

 Dose.— D., TTivii.-xxx. (.42-2.). 



A saturated solution of phosphorus in alcohol may be made by dis- 

 solving .312 parts of phosphorus in 100 parts of absolute alcohol. 

 . Dose.— H., IssA. (15.-30.). 



ACTION OF PHOSPHORUS. 



Internal. — All that is certainly known of phosphorus 

 concerns its effect upon the growth of bone. It has been 

 proven experimentally that phosphorus stimulates the 

 formation of bone, making the spongy tissue in the long and 

 short bones thicker, and the compact tissue denser. If lime 

 is abstracted from the food, the new growth of bone is of a 

 gelatinous consistency. 



Phosphate of lime increases more markedly the earthy 

 constituents of bone. Phosphorus exists to a considerable 

 extent as a component part of nerve tissue, as well as bone, 

 and is to a less degree a constituent of other tissues. It is 

 thought that phosphorus acts as a stimulant to the nutrition 

 of those tissues of which it is a constituent part. In man, 

 large therapeutic doses of phosphorus frequently occasion 

 sexual excitement, increased force and rapidity of the pulse, 

 mental exhilaration and capacity for work. There is 

 abundant clinical evidence to indicate that phosphorus is a 

 nerve stimulant and tonic, but whether it is a general 

 diffusible stimulant is not so certain. The therapeutic 

 action of phosphorus differs decidedly from its toxic effect. 

 Phosphorus enters the blood in part as phosphorus, in the 



