MOltPHINE HYDROCHLORATE 335 



having a bitter taste ; permanent in the air ; soluble in 4,350 

 parts of water. 



Dose. — Same as salts of morphine, but the latter are 

 preferable on account of their solubility. 



Morphine Hydrochlora.s. Morphine Hydrochlorate. 

 C,,H,,N O3H CI + 3 H,0. (U. S. & B. P.) 



Derivation. — Morphine is stirred with hot distilled 

 water, to which hydrochloric acid is gradually added. Mor- 

 phine hydrochlorate crystallizes out on cooling. 



Properties. — White, feathery needles of a silky lustre ; 

 or minute, colorless, needle-shaped crystals ; odorless and 

 having a bitter taste. Permanent in the air. Soluble in 24 

 parts of water and in 62 parts of alcohol. Very slightly 

 soluble in ether or chloroform. 



Incompatibility. — Incompatible with all agents containing 

 tannin, alkaline carbonates, lime water, salts of copper, mer- 

 cury, zinc and lead ; and with Fowler's solution of arsenic. 



Dose.—B., & C, gr.iii.-x. (.2-.6) ; Sb., gr.ss.-ii. (.03-.12) ; 

 Sw., gr.-J^-i (.006-03); D., gr.|4 (.008-03). 



Subcutaneously.— H., gr.iii.-iv. (.2-24); D., gr.i-| (.008.- 

 .02). 



124- parts of morphine hydrochlorate correspond to 

 100 parts of morphine. 



Morphine Acetas. Morphine Acetate. 

 C.H^eN 03C,H,0, 4 3 H,0. (U. S. k B. P.) 



Derivation. — Morphine is dissolved in acetic acid and 

 water, and the solution evaporated and crystallized. 



Properties. — A white, or faintly yellowish- white, crystal- 

 line, amorphous powder, having a faint, acetous odor and 

 bitter taste. It slowly loses acetic acid on exposure to the 

 air, and should be kept in dark, amber-colored, well:Stop- 

 pered vials. Soluble, when freshly prepared, in 2.5 parts of 

 water, and in 47.6 parts of alcohol. 



Dose, — Same as morphine hydrochlorate. 



